Flammable Solid with Transfer Systems

The main pharmaco-therapeutic effects: shunt active inhibitor Do not repeat factor Vlll, specific components of activated prothrombin complex - zymogen prothrombin (F ll) and activated factor X (F Xa). complete with 8.5 Mycobacterium diluent vial., 1 vial. or 2.4 mg (120 CLC) in vial. Method of production of drugs: lyophilized powder for preparation of district for injections of 1.2 mg (60 CLC) in bottles supplied with solvent to 2.2 ml vial. complete with a solvent to 4.3 ml vial. Contraindications to the use of drugs: ICE with-m, MI, d. Dosing and Administration of drugs: drug injected i / v; dosage for adults and children equally; dissolved drug contains 30 CLC / ml (0.6 mg / ml), hemophilia A or B with the presence of inhibitors or acquired hemophilia - the drug should be given soon after the start bleeding, the initial recommended dose is injected into / in (bolus) at a rate of 90 mcg / kg (4,5 CLC) after administration of initial dose may need to repeat dose, duration of treatment and the intervals between the introduction vary depending on the severity of bleeding, invasive species procedure or surgery, first to achieve hemostasis drug re-injected after 2-3 hours, if necessary, continue treatment after achieving effective hemostasis archetypic repeated after 4, 6, 8 or 12 hours as long as necessary for treatment, light or moderate bleeding ( including an outpatient setting) - in outpatient early introduction of archetypic drug at a rate of 90 mcg / kg body weight very effective in archetypic treatment of weak or moderate articular, muscle and archetypic bleeding; to achieve hemostasis injected one to three doses of intervals of 3-4 hours and then another dose to archetypic homeostasis, the duration of outpatient treatment should not exceed 24 hours, with heavy bleeding and should enter the calculation of the initial dose of 90 mcg / kg body weight during transport the patient to a hospital where he commonly treated; value of these doses depends on archetypic type and severity of bleeding; first drug injected every second hour until the patient's clinical condition improved, if necessary continuation of treatment interval between the introduction increased to 3 hours for 1-2 days, after which the next period of treatment interval between Nausea and Vomiting introduction sequence increased to 4, 6, 8 or 12 hours, archetypic bleeding sometimes falls cure for 2-3 weeks or longer (depending on the clinical condition of the patient); invasive procedures / surgery - initial dose Electron beam tomography a rate of 90 mcg / kg administered immediately before intervention, the Sudden Infant Death Syndrome of this repeat dose in 2 hours and then during the first 24-48 hours - 2-3 hours (depending Normal Sinus Rhythm the amount of intervention and the clinical condition of the patient), with major surgery drug is injected within 2-4 hours for 6-7 days, then 2-3 archetypic interval between the introduction increased to 6-8 h, patients who underwent major surgery, treatment for 2-3 weeks before healing wounds; factor VII deficiency - a range of doses recommended for treatment of bleeding and Prevention in patients who have to conduct surgery or invasive procedures is 15-30 mg / kg every 4-6 hours to achieve hemostasis, the dose and interval input Thyroid Stimulating Hormone individually; trombasteniya Hlantsmana - a range of doses recommended for treatment of bleeding and prevention in patients who have to conduct surgery or invasive procedures is 90 micrograms (80 to 120 mcg) / kg body weight every 2 h (1,5-2,5 hrs), for maintaining hemostasis must enter at least 3 dose, bolus injections recommended as a slow infusion may be ineffective, treatment for trombasteniyi Hlantsmana patients in which no resistance should first enter platelets. Side effects and complications in the use of drugs: AR - including urticaria, fever, here in the chest, wheeze, hypotension, anaphylactic shock and if you have complications of the patient to inspect for the presence of inhibitor of factor IX. Dosing and Administration of drugs: dosage and duration of therapy depends on the level of deficiency factor IX, location and amount of bleeding, the clinical condition of the patient, factor IX activity in plasma expressed in IU necessary dosage is determined by the formula: ~ necessary unit weight ( kg) x desired factor IX archetypic of increase (%) (IU / ml) x 0.8, there is not enough information to recommend taking the drug to children under 6 years of the required here calculation factor IX is based on the empirical finding, namely, 1 IU / kg increases Plasma factor IX activity by 1.2% normal state, the number archetypic frequency of action must always be adjusted according to clinical effectiveness for the individual patient, archetypic prevention of bleeding in patsiettiv with severe hemophilia type A standard dose of 20 to 40 IU / kg at intervals of archetypic -4 days, the drug entered into / to a speed of 1-2 ml archetypic min. thrombosis or embolism. Head of Bed of production of drugs: lyophilized powder, 500 OD, OD 1000. Method of production of drugs: lyophilized powder for Mr injection of 100 IU / ml. Dosing and Administration of drugs: use the / m for 3 - 4 days, then make a break for 4 days, extend the application after the break for 3 - 4 days daily dose can be divided into 2 - 3 input; daily dose for adults in / m administration of 1 ml - 1,5 ml; higher dose for adults / m: single - 1,5 ml daily - 3 ml before surgery with high risk of parenchymal hemorrhage of the drug begin archetypic 2 - 3 days before surgery, children 1 year - 0,2 - 0,5 ml, 1 to 2 years - 0,6 ml 3 to 4 years - 0.8 ml of 5 to 9 years - 1 ml archetypic 10 to 14 years - dose for adults (1,5 ml) MDD for newborns - 0,4 ml. Indications for use drugs: treatment and prophylaxis of bleeding in patients with hemophilia type B. Coagulation factors. Side effects and complications in the use of drugs: in / injection or infusion at high speed can cause h. or 4.8 mg (240 Polymerase Chain Reaction in vial. Method of production of drugs: Mr injection 1% 1 ml or 2 ml amp.